LOINC Code 72313-0: t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript Molgen (Bld/Tiss) [# ratio]

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript. It is commonly used with the system or sample type Bld/Tiss.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both
• Method: Molgen

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method
• t(4;11)(q21.3;q23)(AFF1,MLL) fusion transcript/control transcript
• A translocation involving chromosomes 4 and 11, t(4;11)(q21.3;q23), results in a fused transcript between AFF1 and MLL genes. The AFF1-MLL fusion gene is associated with childhood and adult acute lymphoblastic leukemia (ALL) as well as infant acute leukemia. This code is based on, but not limited to, Ispogen's FusionQuant® kit, which uses real-time Quantitative RQ-PCR to quantify the expression level of specific AFF1-MLL fusion transcripts relative to a control gene transcript (e.g. ABL1). Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
• ABL; ABL1; ABL1 transcript; AF4; ALL1; ALL-1; Blood; control gene; DNA; FEL; gene fusion; gene translocation; Genetics; Heredity; Heritable; Homolog of trithorax; HRX; HTRX; HTRX1; Inherited; MLLT2; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.TRANSLOCATION; myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila)); Number ratio; PCR; Point in time; QNT; Quan; Quant; Quantitative; Random; RNA; T prime; t(4,11)(MLLT2,MLL) gene translocation; t(4;11)(AFF1,MLL); Tissue; Tissue, unspecified; translocation; TRX1; WB; Whole blood; Whole blood or Tissue

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions