What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveBoth

LOINC Code 74486-2: Cytokeratin 5 and p63 and Cytokeratin AE1 Ag Immune stain Nom (Tiss)

Name: LOINC Code 74486-2: Cytokeratin 5 and p63 and Cytokeratin AE1 Ag Immune stain Nom (Tiss)
Creator: HealthAssure Clinical Team
Published: 2026-05-21T08:59:53.976Z

74486-2 is a LOINC code used to identify Cytokeratin 5 and p63 and Cytokeratin AE1 Ag Immune stain Nom (Tiss) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Cytokeratin 5 & p63 & Cytokeratin AE1 Ag. It is commonly used with the system or sample type Tiss.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Cytokeratin 5 & p63 & Cytokeratin AE1 Ag. It is commonly used with the system or sample type Tiss.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Both
Method: Immune stain

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Cytokeratin 5 and p63 and Cytokeratin AE1 Ag [Identifier] in Tissue by Immune stain
Cytokeratin 5 & p63 & Cytokeratin AE1 Ag
Breast triple stain (CK5/p63/CK AE1) useful in differentiation of ductal carcinoma in situ (DCIS) from microinvasive breast carcinoma as well as radial scars (benign breast lesions) from infiltrating carcinoma.
Antigen; Antigens; Autoimmune hepatitis; CK; CK5; CK5+p63+CK AE1; Identity or presence; IHC; Imm; Immunohistochemical stain; Immunostain; ImStn; Imun; Imune; LMW; Nominal; Pathology; Point in time; Random; St; Stains; Stn; Tissue; Tissue, unspecified

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Cytokeratin 5 and p63 and Cytokeratin AE1 Ag Immune stain Nom (Tiss)Cytokeratin 5 and p63 and Cytokeratin AE1 Ag [Identifier] in Tissue by Immune stainCK5+p63+CK AE1 Ag Tiss ImStnCytokeratin 5 & p63 & Cytokeratin AE1 AgPATHCytokeratin 5 and P63 and Cytokeratin AE1 antigen, TissuePrid

Frequently asked questions

Code details

Code74486-2

SystemLOINC

Display nameCytokeratin 5 and p63 and Cytokeratin AE1 Ag Immune stain Nom (Tiss)

DescriptionCytokeratin 5 & p63 & Cytokeratin AE1 Ag

Short nameCK5+p63+CK AE1 Ag Tiss ImStn

ComponentCytokeratin 5 & p63 & Cytokeratin AE1 Ag

PropertyPrid

TimingPt

System (specimen)Tiss

ScaleNom

MethodImmune stain

ClassPATH

StatusACTIVE

Order/ObservationBoth

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.48

Last changed2.48

Consumer names

Cytokeratin 5 and P63 and Cytokeratin AE1 antigen, Tissue

Part names

Cytokeratin 5 & p63 & Cytokeratin AE1 AgPridPtTissNomImmune stainCytokeratin 5 and p63 and Cytokeratin AE1 AgPresence or IdentityPoint in time (spot)Tissue and Smears

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.