LOINCActiveBoth

LOINC Code 74676-8: Carbapenemase Carba NP Nom (Isol)

74676-8 is a LOINC code used to identify Carbapenemase Carba NP Nom (Isol) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Carbapenemase. It is commonly used with the system or sample type Isolate.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Carbapenemase. It is commonly used with the system or sample type Isolate.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both
  • Method: Carbapenemase Nordmann-Poirel

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Carbapenemase [Type] in Isolate by Carba NP
Carbapenemase
The Carba NP (Carbapenemase Nordmann-Poirel) test rapidly (<2 hrs) detects carbapenemase production in isolates of Enterobacteriaceae and Pseudomonas aeruginosa. Carbapenemases are detected and can be differentiated by the CarbaNP test when the test isolate produces the enzyme (in the absence of a chemical inhibitor) that hydrolyzes imipenem (a carbapenem antibiotic) into the carboxylic form of the antibiotic, thereby lowering the pH of the reaction solution which contains phenol red indicator. The acidification changes the red color of the reaction solution to orange-yellow color (positive result) that can be visualized easily with the naked eye. Carba NP testing can detect the following carbapenemase typesKlebsiella pneumoniae carbapenemase (KPC; Ambler class A); Verona integron-encoded metallo-β-lactamase (VIM), imipenemase (IMP), New Delhi metallo-β-lactamase (NDM) (all Ambler class B); and oxacillinase-48 (OXA-48; Ambler class D). For this test, each test isolate is inoculated into 4 reaction wells or tubes: one without any antibiotic or chemical inhibitor against carbapenemases, one containing imipenem without any chemical inhibitor, one containing impenem and tazobactam (which inhibits KPC carbapenemases), one containing imipenem and EDTA (which inhibits VIM, IMP, and NDM carbapenemases). Based on the presence and absence of color change among the 4 reaction wells or tubes, one can differentiate among the 3 classes of carbapenemases. However, differentiation is not possible with this test in isolates that produce more than one class of carbapenemases simultaneously.
carbapenem-resistant Klebsiella pneumoniae; CRE; CRKP; Hodge test; ID; Infectious Disease; InfectiousDisease; Islt; Isol; Microbiology; Nominal; Point in time; Random; Typ

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Carbapenemase Carba NP Nom (Isol)Carbapenemase [Type] in Isolate by Carba NPCarbapenemase IsltCarbapenemaseMICROTypePt

Frequently asked questions

Code details

Code74676-8
SystemLOINC
Display nameCarbapenemase Carba NP Nom (Isol)
DescriptionCarbapenemase
Short nameCarbapenemase Islt
ComponentCarbapenemase
PropertyType
TimingPt
System (specimen)Isolate
ScaleNom
MethodCarbapenemase Nordmann-Poirel
ClassMICRO
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.48
Last changed2.73

Consumer names

Carbapenemase

Part names

CarbapenemaseTypePtIsolateNomCarbapenemase Nordmann-PoirelPoint in time (spot)Carba NP

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 74676-8 | HealthAssure