LOINCActiveOrder

LOINC Code 75881-3: Lupus anticoagulant three screening tests W Reflex panel Coag (PPP)

75881-3 is a LOINC code used to identify Lupus anticoagulant three screening tests W Reflex panel Coag (PPP) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Lupus anticoagulant three screening tests W Reflex panel. It is commonly used with the system or sample type PPP.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Lupus anticoagulant three screening tests W Reflex panel. It is commonly used with the system or sample type PPP.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Order
  • Panel type: Panel
  • Method: Coag

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex
Lupus anticoagulant three screening tests W Reflex panel
The lupus anticoagulant three screen panel is based primarily on the 2009 International Society of Thrombosis and Haemostasis (ISTH) and 2014 Clinical and Laboratory Standards Institute (CLSI) guidelines for detecting the presence of lupus anticoagulants (LA), with some modifications based on information from major laboratories that use three screening tests (PT, aPTT and dRVVT) as the first step in LA testing. The ISTH guidelines recommend using dRVVT as the first screening test and aPTT-LA as the second screening test, followed by reflex to mixing studies with 11 Pooled Normal Plasma and confirmatory testing with excess phospholipid (PL) if either of the screening tests are positive. The CLSI guidelines permit use of other screening tests in addition to aPTT and dRVVT, and also recommend changing the order of the tests to screening following by confirmatory and then mixing. Some major laboratories reflex to thrombin time (TT) and reptilase assays if any of the three screening tests have an abnormal result, so both of those tests are included in the panel. Both ISTH and CLSI recommend reporting quantitative results as the ratio of the patient result to the control result for each of the screening, mixing and confirmatory tests that are performed. However, they use different parameters for the control: ISTH recommends calculating the control based on pooled normal plasma (PNP), while CLSI recommends using the mean of the reference interval provided by the assay manufacturer. Many labs report either the actual patient result or the actual patient result and the actual/normal ratio, so we have included both options in the panel. In addition to the quantitative results, both guidelines recommend reporting a qualitative interpretation.
3; Anticoag; Anti-phospholipid antibody; Asympt; Asymptomatic; Clot; Clottable; COAGULATION; Coagulation assay; Coagulation inhibiting antibody; dRVVT; LA; LA 3 screen W Reflex; LAC; Lupus inhibitor; Pan; PANEL.COAGULATION; Panl; Plas; Platelet poor plasma; Pnl; Point in time; Random; Scn; Tilt tube

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Lupus anticoagulant three screening tests W Reflex panel Coag (PPP)Lupus anticoagulant aPTT, dRVVT and PT screening panel W ReflexLA aPTT+dRVVT+PT W Reflex PPPLupus anticoagulant three screening tests W Reflex panelPANEL.COAGLupus Anticoagulant Three Screening Tests W Reflex Panel, Blood-

Frequently asked questions

Code details

Code75881-3
SystemLOINC
Display nameLupus anticoagulant three screening tests W Reflex panel Coag (PPP)
DescriptionLupus anticoagulant three screening tests W Reflex panel
Short nameLA aPTT+dRVVT+PT W Reflex PPP
ComponentLupus anticoagulant three screening tests W Reflex panel
Property-
TimingPt
System (specimen)PPP
Scale-
MethodCoag
ClassPANEL.COAG
StatusACTIVE
Order/ObservationOrder

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.50
Last changed2.67

Consumer names

Lupus Anticoagulant Three Screening Tests W Reflex Panel, Blood

Part names

Lupus anticoagulant three screening tests W Reflex panel-PtPPPCoagPoint in time (spot)Platelet poor plasmaCoagulation assay

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 75881-3 | HealthAssure