LOINC Code 77173-3: Hepatocyte growth factor receptor Ag Immune stain Ql (Tiss)

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Hepatocyte growth factor receptor Ag. It is commonly used with the system or sample type Tiss.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both
• Method: Immune stain

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• Hepatocyte growth factor receptor Ag [Presence] in Tissue by Immune stain
• Hepatocyte growth factor receptor Ag
• The stain is interpreted as positive if 50% or more of the tumor cells show moderate to strong (2+, 3+) membranous staining, indicating MET amplification. MET amplification (positive) has been seen in approximately 22% of non-small-cell lung cases with acquired resistance to anti-EGFR inhibitors. Recent Phase II clinical trails (OAM4558g) results were released at ASCO in 2011 showed that patients who were c-MET positive (2+ or 3+) lived twice as long without disease progression (PFS) when they received MetMAb therapy in combination with erlotinib versus receiving erlotinib alone.
• Antigen; Antigens; c-Met; Fac; Fact; Hepatopoietin A; HGF; HGFR; IHC; Imm; Immunohistochemical stain; Immunostain; ImStn; Imun; Imune; mesenchymal-epithelial transition; MET; Ordinal; PATHOLOGY; Point in time; PR; QL; Qual; Qualitative; Random; Rec; Recept; Receptors; Recp; Recptr; Scatter factor; Scatter Factor Receptor; Screen; SFR; St; Stains; Stn; Tissue; Tissue, unspecified; Transmembrane tyrosine kinase receptor; Tyrosine-protein kinase Met

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions