LOINCActiveObservation

LOINC Code 77353-1: Noninvasive colorectal cancer DNA and occult blood screening Nar (Stl) [Interp]

77353-1 is a LOINC code used to identify Noninvasive colorectal cancer DNA and occult blood screening Nar (Stl) [Interp] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Noninvasive colorectal cancer DNA+occult blood screening. It is commonly used with the system or sample type Stool.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Noninvasive colorectal cancer DNA+occult blood screening. It is commonly used with the system or sample type Stool.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Observation

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Noninvasive colorectal cancer DNA and occult blood screening [Interpretation] in Stool Narrative
Noninvasive colorectal cancer DNA+occult blood screening
This term was created for, but is not limited in use to, Exact Sciences' Cologuard DNA screening test for colorectal cancer. The Cologuard algorithm includes two laboratory procedures performed on a single stool specimen1) detection and quantification of fecal occult blood using ELISA; and 2) detection of multiple genetic biomarkers (NDRG4 and BMP3 methylation targets, seven KRAS point mutations, and beta actin as a proxy for the total amount of human DNA in each sample) using magnetic bead based oligonucleotide hybrid capture to isolate the biomarkers followed by quantitative real-time target and signal amplification. The occult blood and genetic biomarker results are subsequently entered into a logistic regression model, and the results from this model are used to calculate a composite score from which the final binary result (positive, negative) is determined. [PMID: 24645800]
Asympt; Asymptomatic; Bowel movement; Deoxyribonucleic acid; Faecal; Faeces; Fecal; Feces; Impression; Impression/interpretation of study; Impressions; Interp; Interpretation; Molecular pathology; MOLPATH; Narrative; Noninv colon ca DNA+occ bld screen; Occ; Point in time; Random; Report; Scn; Stl; Stool = Fecal

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Noninvasive colorectal cancer DNA and occult blood screening Nar (Stl) [Interp]Noninvasive colorectal cancer DNA and occult blood screening [Interpretation] in Stool NarrativeNoninv colon ca DNA+occ bld scrn Stl-ImpNoninvasive colorectal cancer DNA+occult blood screeningMOLPATHInterpretation of Noninvasive Colorectal Cancer DNA and Occult Blood Screening test result, StoolImp

Frequently asked questions

Code details

Code77353-1
SystemLOINC
Display nameNoninvasive colorectal cancer DNA and occult blood screening Nar (Stl) [Interp]
DescriptionNoninvasive colorectal cancer DNA+occult blood screening
Short nameNoninv colon ca DNA+occ bld scrn Stl-Imp
ComponentNoninvasive colorectal cancer DNA+occult blood screening
PropertyImp
TimingPt
System (specimen)Stool
ScaleNar
ClassMOLPATH
StatusACTIVE
Order/ObservationObservation

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.52
Last changed2.73

Consumer names

Interpretation of Noninvasive Colorectal Cancer DNA and Occult Blood Screening test result, Stool

Part names

Noninvasive colorectal cancer DNA+occult blood screeningImpPtStoolNarNoninvasive colorectal cancer DNA and occult blood screeningImpression/interpretation of studyPoint in time (spot)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 77353-1 | HealthAssure