What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveBoth

LOINC Code 77621-1: Natriuretic peptide.B prohormone N-Terminal IA (Pleur fld) [Mass/Vol]

Name: LOINC Code 77621-1: Natriuretic peptide.B prohormone N-Terminal IA (Pleur fld) [Mass/Vol]
Creator: HealthAssure Clinical Team
Published: 2026-05-21T08:59:58.754Z

77621-1 is a LOINC code used to identify Natriuretic peptide.B prohormone N-Terminal IA (Pleur fld) [Mass/Vol] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Natriuretic peptide.B prohormone N-Terminal. It is commonly used with the system or sample type Plr fld.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Natriuretic peptide.B prohormone N-Terminal. It is commonly used with the system or sample type Plr fld.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Both
Method: IA

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay

Natriuretic peptide.B prohormone N-Terminal

Brain natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) are significantly elevated in patients with heart failure because tension or stretching of the cardiac wall, such as occurs with heart failure, stimulates the synthesis of natriuretic peptides. Pleural fluid BNP and NT-proBNP is a useful biomarker for pleural effusions secondary to heart failure. A pleural NT-proBNP cutoff value of 1,165 pg/mL had a sensitivity of approximately 95% for discriminating heart failure-related effusions from exudates, and a cutoff of 2,300 pg/mL had a sensitivity of approximately 70% for discriminating heart failure-related transudates from non-heart-failure related pleural effusions. [PMID22710710] This term was created for, but is not restricted in use to, the Elecsys proBNP II assay, which contains two monoclonal antibodies that recognize epitopes located in the N-terminal part (1-76) of proBNP (1-108).

Beta Natriuretic Peptide; BNP; Brain Natriuretic Peptide; B-type natriuretic peptide; Chemistry; EIA; ELFA; ELISA; Enzyme immunoassay; IAA; Level; Mass concentration; MEIA; Natriutietic peptide.B; NTproBNP; NT-proBNP; Pept; Pleural; Pleural fluid; Point in time; proBNP; Pro-brain natriuretic peptide; QNT; Quan; Quant; Quantitative; Random; SUDS; thoracentesis fluid

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Natriuretic peptide.B prohormone N-Terminal IA (Pleur fld) [Mass/Vol]Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by ImmunoassayNT-proBNP Plr IA-mCncNatriuretic peptide.B prohormone N-TerminalCHEMNatriuretic Peptide.B Prohormone N-Terminal, Pleural fluidMCnc

Frequently asked questions

Code details

Code77621-1

SystemLOINC

Display nameNatriuretic peptide.B prohormone N-Terminal IA (Pleur fld) [Mass/Vol]

DescriptionNatriuretic peptide.B prohormone N-Terminal

Short nameNT-proBNP Plr IA-mCnc

ComponentNatriuretic peptide.B prohormone N-Terminal

PropertyMCnc

TimingPt

System (specimen)Plr fld

ScaleQn

MethodIA

ClassCHEM

Example unitsng/L

StatusACTIVE

Order/ObservationBoth

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.52

Last changed2.56

Consumer names

Natriuretic Peptide.B Prohormone N-Terminal, Pleural fluid

Part names

Natriuretic peptide.B prohormone N-TerminalMCncPtPlr fldQnIAMass ConcentrationPoint in time (spot)Pleural fluidImmunoassay

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.