LOINCActiveObservation

LOINC Code 80181-1: S-adenosylmethionine and S-adenosylhomocystine pattern Nar [Interp]

80181-1 is a LOINC code used to identify S-adenosylmethionine and S-adenosylhomocystine pattern Nar [Interp] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component S-adenosylmethionine & S-adenosylhomocystine pattern. It is commonly used with the system or sample type Ser/Plas.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component S-adenosylmethionine & S-adenosylhomocystine pattern. It is commonly used with the system or sample type Ser/Plas.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Observation

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

  • S-adenosylmethionine and S-adenosylhomocystine pattern [Interpretation] in Serum or Plasma Narrative
  • S-adenosylmethionine & S-adenosylhomocystine pattern
  • S-adenosylhomocysteine (SAH) and S-adenosylmethionine (SAM) levels are measured when investigating folate and vitamin B12 deficiency, and the ratio of SAH to SAM is also used as a measure of methylation status. Low levels of SAM have also been associated with depression, dementia, vacuolar myelopathy and liver disease.
  • Adenosylmethionine; Chemistry; Dementias; Depression, Emotional; Impression; Impression/interpretation of study; Impressions; Interp; Interpretation; Narrative; Pl; Plasma; Plsm; Point in time; Random; Report; S prime; S-Adenosyl Methionine; SAMe; SAM-e; SAMe and SAH pattern; Sammy; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

S-adenosylmethionine and S-adenosylhomocystine pattern Nar [Interp]S-adenosylmethionine and S-adenosylhomocystine pattern [Interpretation] in Serum or Plasma NarrativeSAMe and SAH pattern SerPl-ImpS-adenosylmethionine & S-adenosylhomocystine patternCHEMInterpretation of S-adenosylmethionine and S-adenosylhomocystine pattern test result, BloodImp

Frequently asked questions

Code details

Code80181-1
SystemLOINC
Display nameS-adenosylmethionine and S-adenosylhomocystine pattern Nar [Interp]
DescriptionS-adenosylmethionine & S-adenosylhomocystine pattern
Short nameSAMe and SAH pattern SerPl-Imp
ComponentS-adenosylmethionine & S-adenosylhomocystine pattern
PropertyImp
TimingPt
System (specimen)Ser/Plas
ScaleNar
ClassCHEM
StatusACTIVE
Order/ObservationObservation

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.54
Last changed2.54

Consumer names

Interpretation of S-adenosylmethionine and S-adenosylhomocystine pattern test result, Blood

Part names

S-adenosylmethionine & S-adenosylhomocystine patternImpPtSer/PlasNarS-adenosylmethionine and S-adenosylhomocystine patternImpression/interpretation of studyPoint in time (spot)Serum or Plasma

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 80181-1 | HealthAssure