What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveBoth

LOINC Code 82367-4: Peripheral deiodinase activity Calculated by SPINA [Moles/Time]

Name: LOINC Code 82367-4: Peripheral deiodinase activity Calculated by SPINA [Moles/Time]
Creator: HealthAssure Clinical Team
Published: 2026-05-21T09:00:08.165Z

82367-4 is a LOINC code used to identify Peripheral deiodinase activity Calculated by SPINA [Moles/Time] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Peripheral deiodinase activity. It is commonly used with the system or sample type Ser/Plas.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Peripheral deiodinase activity. It is commonly used with the system or sample type Ser/Plas.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Both
Method: Calculated.SPINA

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Peripheral deiodinase activity [Moles/time] in Serum or Plasma by Calculated.SPINA

Peripheral deiodinase activity

The sum activity of peripheral deiodinases (GD, also referred to as deiodination capacity or total deiodinase activity) is the maximum amount of triiodothyronine (T3) produced per time-unit by deiodinases outside the central nervous system. The structure parameter inference approach (SPINA) uses Michaelis-Menten functions and pharmakokinetic data to estimate GD under conditions of substrate saturation. One calculation is based on peripheral free T3 and free T4 values, and an alternate calculation uses peripheral total T3 and free T4. GD calculated using the SPINA approach is also known as SPINA-GD. SPINA-GD may be useful in diagnosing thyroid conditions that are difficult to diagnose based on traditional thyroid function studies, such as subclinical forms of thyroid failure, hypothalamic or pituitary dysfunction, and non-thyroidal illness syndrome. [PMID27375554] Thyroid secretory function by SPINA, called SPINA-GT, is a related result [LOINC: 82368-2].

Activ; Actvty; Calc; Calc SPINA; Calculation; Chemistry; Deiodination capacity; Movements; Per deiod act; Periph; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SPINA-GD; SR; sRate; Substance Rate; Total deiodinase activity

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Peripheral deiodinase activity Calculated by SPINA [Moles/Time]Peripheral deiodinase activity [Moles/time] in Serum or Plasma by Calculated.SPINAPer deiod act SerPl Calc SPINA-sRatePeripheral deiodinase activityCHEMPeripheral deiodinase activity, BloodSRat

Frequently asked questions

Code details

Code82367-4

SystemLOINC

Display namePeripheral deiodinase activity Calculated by SPINA [Moles/Time]

DescriptionPeripheral deiodinase activity

Short namePer deiod act SerPl Calc SPINA-sRate

ComponentPeripheral deiodinase activity

PropertySRat

TimingPt

System (specimen)Ser/Plas

ScaleQn

MethodCalculated.SPINA

ClassCHEM

Example unitsnmol/s

StatusACTIVE

Order/ObservationBoth

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.58

Last changed2.58

Consumer names

Peripheral deiodinase activity, Blood

Part names

Peripheral deiodinase activitySRatPtSer/PlasQnCalculated.SPINASubstance RatePoint in time (spot)Serum or Plasma

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.