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LOINC Code 82720-4: NK cell cytotoxicity panel (Bld MC)

82720-4 is a LOINC code used to identify NK cell cytotoxicity panel (Bld MC) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Natural killer cell cytotoxicity panel. It is commonly used with the system or sample type Bld MC.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Natural killer cell cytotoxicity panel. It is commonly used with the system or sample type Bld MC.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Order
  • Panel type: Panel

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Natural killer cell cytotoxicity panel - Blood mononuclear cells
Natural killer cell cytotoxicity panel
The natural killer (NK) cytotoxicity profile assesses the functionality of natural killer cells and is used to evaluate patients with various conditions, including recurrent herpes viral infections, hemophagocytic lymphohistiocytosis, and suspected or known monogenic defects. The NK cytotoxicity profile is also used for the evaluation of immune reconstitution post hematopoietic cell transplantation and post immunomodulatory therapy. Peripheral blood mononuclear cells (PBMCs) are used as the specimen for NK cytotoxicity assays because the cytotoxicity of the MC population is predominantly due to NK cells. In the cytotoxicity assay, samples of the patient's mononuclear cells (called 'effector cells' or E cells') are incubated with labeled target cells ('T cells') in a series of predetermined ratios, for example, 1001 E to T, 50:1 E to T, 25:1 E to T. Cytotoxicity is measured as the amount of label released when the target cell is destroyed, and the percent cytotoxicity for a given E:T ratio is the ratio of label released when all of the target cells are destroyed using a cell lysis detergent as an experimental control. Several features of the cytotoxicity profile are important, including the maximum cytotoxicity, the relative difference between the maximum and the minimum, and the change in percent cytotoxicity between sequential dilutions. Different patterns of these measures may be associated with different disease processes. Cytotoxicity may also be reported in terms of lytic units [LOINC: 34439-0], meaning the number of E cells needed to lyse a certain number of target cells.
Blood; HEMATOLOGY/CELL COUNTS; NK; NK cytotox Pnl; NK cytotoxicity; Pan; PANEL.HEMATOLOGY& CELL COUNTS; Panl; PBMC; Peripheral blood mononuclear cells; Pnl; Point in time; Random; WB; Whole blood

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

NK cell cytotoxicity panel (Bld MC)Natural killer cell cytotoxicity panel - Blood mononuclear cellsNK cytotox Pnl Bld MCNatural killer cell cytotoxicity panelPANEL.HEM/BCNK cell cytotoxicity panel, Blood-

Frequently asked questions

Code details

Code82720-4
SystemLOINC
Display nameNK cell cytotoxicity panel (Bld MC)
DescriptionNatural killer cell cytotoxicity panel
Short nameNK cytotox Pnl Bld MC
ComponentNatural killer cell cytotoxicity panel
Property-
TimingPt
System (specimen)Bld MC
Scale-
ClassPANEL.HEM/BC
StatusACTIVE
Order/ObservationOrder

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.58
Last changed2.64

Consumer names

NK cell cytotoxicity panel, Blood

Part names

Natural killer cell cytotoxicity panel-PtBld MCPoint in time (spot)Blood mononuclear cells

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 82720-4 | HealthAssure