What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveObservation

LOINC Code 83054-7: PD-L1 by clone 22C3 Immune stain Nar (Tiss) [Interp]

Name: LOINC Code 83054-7: PD-L1 by clone 22C3 Immune stain Nar (Tiss) [Interp]
Creator: HealthAssure Clinical Team
Published: 2026-05-21T09:00:10.306Z

83054-7 is a LOINC code used to identify PD-L1 by clone 22C3 Immune stain Nar (Tiss) [Interp] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Programmed cell death ligand 1 by clone 22C3. It is commonly used with the system or sample type Tiss.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Programmed cell death ligand 1 by clone 22C3. It is commonly used with the system or sample type Tiss.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Observation
Method: Immune stain

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

PD-L1 by clone 22C3 [Interpretation] in Tissue by Immune stain Narrative

Programmed cell death ligand 1 by clone 22C3

This term should be used to report the narrative impression of PD-L1 (CD274) protein expression in tumor cells as determined by immune staining with anti-PD-L1 clone 22C3. Patients with certain cancers, such as non-small cell lung cancer (NSCLC), whose tumors are positive for PD-L1 by 22C3 may be eligible for anti-programmed death 1 (PD-1) receptor antibody therapy, which effectively prevents the binding of PD-L1 to PD-1. The percentage of viable tumor cells that show partial or complete PD-L1 membrane staining is reported using [LOINC83053-9], and the ordinal result for PD-L1 expression using [LOINC: 83052-1]. This term was created for, but is not limited in use to, the Dako PD-L1 22C3 pharmDx test kit, which, as of November 2016, is FDA-approved as a companion diagnostic to assess whether patients with specific cancers are eligible for pembrolizumab therapy.

B7 homolog 1; B7-H1; CD274; Cluster of differentiation 274; i; IHC; Imm; Immunohistochemical stain; Immunostain; Impression; Impression/interpretation of study; Impressions; ImStn; Imun; Imune; Interp; Interpretation; Narrative; Pathology; PDL1; PD-L1; PD-L1 by 22C3; Point in time; Random; Report; St; Stains; Stn; Tissue; Tissue, unspecified

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

PD-L1 by clone 22C3 Immune stain Nar (Tiss) [Interp]PD-L1 by clone 22C3 [Interpretation] in Tissue by Immune stain NarrativePD-L1 by 22C3 Tiss ImStn-ImpProgrammed cell death ligand 1 by clone 22C3PATHInterpretation of PD-L1 by clone 22C3 test result, TissueImp

Frequently asked questions

Code details

Code83054-7

SystemLOINC

Display namePD-L1 by clone 22C3 Immune stain Nar (Tiss) [Interp]

DescriptionProgrammed cell death ligand 1 by clone 22C3

Short namePD-L1 by 22C3 Tiss ImStn-Imp

ComponentProgrammed cell death ligand 1 by clone 22C3

PropertyImp

TimingPt

System (specimen)Tiss

ScaleNar

MethodImmune stain

ClassPATH

StatusACTIVE

Order/ObservationObservation

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.58

Last changed2.73

Consumer names

Interpretation of PD-L1 by clone 22C3 test result, Tissue

Part names

Programmed cell death ligand 1 by clone 22C3ImpPtTissNarImmune stainPD-L1 by clone 22C3Impression/interpretation of studyPoint in time (spot)Tissue and Smears

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.