What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveBoth

LOINC Code 83057-0: PD-L1 by clone SP142 Immune stain Ql (Tiss)

Name: LOINC Code 83057-0: PD-L1 by clone SP142 Immune stain Ql (Tiss)
Creator: HealthAssure Clinical Team
Published: 2026-05-21T09:00:10.306Z

83057-0 is a LOINC code used to identify PD-L1 by clone SP142 Immune stain Ql (Tiss) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Programmed cell death ligand 1 by clone SP142. It is commonly used with the system or sample type Tiss.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Programmed cell death ligand 1 by clone SP142. It is commonly used with the system or sample type Tiss.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Both
Method: Immune stain

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

PD-L1 by clone SP142 [Presence] in Tissue by Immune stain

Programmed cell death ligand 1 by clone SP142

This term should be used to report the degree of PD-L1 (CD274) protein expression in tumor cells as determined by immune staining with anti-PD-L1 clone SP142. Patients with certain cancers, such as non small cell lung cancer (NSCLC) or urothelial carcinoma, whose tumors are positive for PD-L1 by SP142, may be eligible for anti-programmed death 1 (PD-1) receptor antibody therapy, which effectively prevents the binding of PD-L1 to PD-1. The percentage of viable tumor cells that show partial or complete PD-L1 membrane staining is reported using [LOINC83053-9]. If at least 50% of tumor cells or at least 10% of inflammatory cells stain positive with SP142, the tumor is considered to have high PD-L1 expression, and if 1 to 50% of tumor cells and 1 to 10% of inflammatory cells stain positive, the tumor has low expression. If <1% of both tumor and inflammatory cells stain positive, the tumor is considered to have no PD-L1 expression. This term was created for, but is not limited in use to, the Ventana PD-L1 (SP142) assay, which, as of November 2016, is FDA-approved as a companion diagnostic to assess whether patients with certain cancers are eligible for atezolizumab therapy.

B7 homolog 1; B7-H1; CD274; Cluster of differentiation 274; i; IHC; Imm; Immunohistochemical stain; Immunostain; ImStn; Imun; Imune; Ordinal; PATHOLOGY; PDL1; PD-L1; PD-L1 by SP142; Point in time; PR; QL; Qual; Qualitative; Random; Screen; St; Stains; Stn; Tissue; Tissue, unspecified

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

PD-L1 by clone SP142 Immune stain Ql (Tiss)PD-L1 by clone SP142 [Presence] in Tissue by Immune stainPD-L1 by SP142 Tiss Ql ImStnProgrammed cell death ligand 1 by clone SP142PATHPD-L1 by Clone SP142, TissuePrThr

Frequently asked questions

Code details

Code83057-0

SystemLOINC

Display namePD-L1 by clone SP142 Immune stain Ql (Tiss)

DescriptionProgrammed cell death ligand 1 by clone SP142

Short namePD-L1 by SP142 Tiss Ql ImStn

ComponentProgrammed cell death ligand 1 by clone SP142

PropertyPrThr

TimingPt

System (specimen)Tiss

ScaleOrd

MethodImmune stain

ClassPATH

StatusACTIVE

Order/ObservationBoth

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.58

Last changed2.73

Consumer names

PD-L1 by Clone SP142, Tissue

Part names

Programmed cell death ligand 1 by clone SP142PrThrPtTissOrdImmune stainPD-L1 by clone SP142Presence or ThresholdPoint in time (spot)Tissue and Smears

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.