What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveObservation

LOINC Code 85380-4: HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp]

Name: LOINC Code 85380-4: HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp]
Creator: HealthAssure Clinical Team
Published: 2026-05-21T09:00:13.315Z

85380-4 is a LOINC code used to identify HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component HIV immunoassay testing algorithm interpretation. It is commonly used with the system or sample type Ser/Plas/Bld.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component HIV immunoassay testing algorithm interpretation. It is commonly used with the system or sample type Ser/Plas/Bld.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Observation

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

HIV immunoassay testing algorithm interpretation in Serum, Plasma or Blood

HIV immunoassay testing algorithm interpretation

This term is used to report the interpretation of results from an HIV immunoassay testing algorithm that may be based on third, fourth, fifth and possibly other generations of HIV immunoassays. HIV testing has evolved significantly in the past 30 years. The first three generations of HIV immunoassays detected HIV antibodies (first IgG only, then IgG and IgM). The fourth-generation tests can detect, but not differentiate between, HIV-1 and HIV-2 antibodies as well as the HIV-1 p24 antigen. The inclusion of the p24 antigen allows for detection of HIV as early as two weeks after exposure and before seroconversion occurs (i.e. before antibodies are produced). In 2014, the U.S. Centers for Disease Control and Prevention published a recommended algorithm for HIV diagnostic testing based on fourth-generation HIV immunoassays [https//stacks.cdc.gov/view/cdc23447]. More recently, fifth-generation HIV immunoassays have been developed, which can detect and differentiate between HIV-1 and HIV-2 antibodies and the HIV-1 p24 antigen. The CDC is in the process of updating its testing algorithm and the latest information can be found at https://www.cdc.gov/hiv/testing/laboratorytests.html. Note that third generation assays are still available in the U.S. and earlier generations may also be available outside the U.S.

AIDS; Blood; HIV IA algorithm interp; HIV imm testing algorithm; Human immunodeficiency virus; ID; Impression; Impression/interpretation of study; Impressions; Infectious Disease; InfectiousDisease; Interp; Interpret; Interpretation; Interpt; Intrp; Microbiology; Nominal; Pl; PlasBld; Plasma; Plsm; Point in time; Random; SerP; SerPl; SerPlas; SerPlBld; Serum; Serum or plasma; Serum, plasma or whole blood; SR; WB; Whole blood

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

HIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp]HIV immunoassay testing algorithm interpretation in Serum, Plasma or BloodHIV IA algorithm interp SerPlBld-ImpHIV immunoassay testing algorithm interpretationMICROHIV immunoassay testing algorithm interpretation, BloodImp

Frequently asked questions

Code details

Code85380-4

SystemLOINC

Display nameHIV immunoassay testing algorithm interpretation (S/P/Bld) [Interp]

DescriptionHIV immunoassay testing algorithm interpretation

Short nameHIV IA algorithm interp SerPlBld-Imp

ComponentHIV immunoassay testing algorithm interpretation

PropertyImp

TimingPt

System (specimen)Ser/Plas/Bld

ScaleNom

ClassMICRO

StatusACTIVE

Order/ObservationObservation

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.61

Last changed2.61

Consumer names

HIV immunoassay testing algorithm interpretation, Blood

Part names

HIV immunoassay testing algorithm interpretationImpPtSer/Plas/BldNomImpression/interpretation of studyPoint in time (spot)Serum, Plasma or Blood

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.