LOINCActiveObservation

LOINC Code 94076-7: Mutations/Megabase (Tumor) [# ratio]

94076-7 is a LOINC code used to identify Mutations/Megabase (Tumor) [# ratio] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Mutations/Megabase. It is commonly used with the system or sample type Tumor.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Mutations/Megabase. It is commonly used with the system or sample type Tumor.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Observation

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Mutations/Megabase [# Ratio] in Tumor
Mutations/Megabase
Tumor mutation/mutational burden (TMB), also known as mutation load, is a biomarker for various cancer types to identify patients who will benefit from immunotherapy, such as immune checkpoint blockade (ICB) therapy.[PMID30395155] Various quantitative and ordinal results may be reported, so it is important to distinguish the type of results when mapping to LOINC. Quantitative results typically include the number of mutations detected per megabase (mut/Mb), often by NGS, in a tumor specimen (this term). The mutations targeted may include non-synonymous or both synonymous and non-synonymous mutations. An ordinal TMB result [LOINC: 94077-5] of high, low, etc., may also be reported to provide an overall interpretation for the quantitative value (muts/Mb). We encourage labs to report how results are determined or calculated in either the structured message format or using another LOINC.
Cancer; Mb; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Mut; Mutation; Muts; Muts/Mb; Number ratio; Point in time; QNT; Quan; Quant; Quantitative; Random; TMB; Tumor mutation burden; Tumor mutational load; tumors; tumour; tumours

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Mutations/Megabase (Tumor) [# ratio]Mutations/Megabase [# Ratio] in TumorMuts/Mb TumorMutations/MegabaseMOLPATH.MUTMutations/Megabase, TumorNRto

Frequently asked questions

Code details

Code94076-7
SystemLOINC
Display nameMutations/Megabase (Tumor) [# ratio]
DescriptionMutations/Megabase
Short nameMuts/Mb Tumor
ComponentMutations/Megabase
PropertyNRto
TimingPt
System (specimen)Tumor
ScaleQn
ClassMOLPATH.MUT
Example unitsmuts/Mb
StatusACTIVE
Order/ObservationObservation

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.67
Last changed2.67

Consumer names

Mutations/Megabase, Tumor

Part names

Mutations/megabaseNRtoPtTumorQnNumber RatioPoint in time (spot)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 94076-7 | HealthAssure