What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveBoth

LOINC Code 94077-5: Tumor mutation burden Ql (Tumor) [Interp]

Name: LOINC Code 94077-5: Tumor mutation burden Ql (Tumor) [Interp]
Creator: HealthAssure Clinical Team
Published: 2026-05-21T09:00:23.054Z

94077-5 is a LOINC code used to identify Tumor mutation burden Ql (Tumor) [Interp] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Tumor mutation burden. It is commonly used with the system or sample type Tumor.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Tumor mutation burden. It is commonly used with the system or sample type Tumor.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Both

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Tumor mutation burden [Interpretation]

Tumor mutation burden

Tumor mutational burden (TMB), also known as mutation load, is a biomarker for various cancer types to identify patients who will benefit from immunotherapy, such as immune checkpoint blockade (ICB) therapy. Testing can be performed by whole exome sequencing (WES) or next-generation sequencing (NGS). Various quantitative and ordinal results may be reported, so it is important to distinguish the type of results when mapping to LOINC. Quantitative results typically include the number of mutations detected per megabase (mut/Mb), often by NGS, in a tumor specimen [LOINC94076-7]. The mutations targeted may include non-synonymous or both synonymous and non-synonymous mutations. Quantitative TMB results have also been reported as the total number of mutations detected by whole exome sequencing (WES). We encourage labs to report how results are determined or calculated in either the structured message format or using another LOINC. An ordinal TMB result (this term) of high, low, etc., may also be reported to provide an overall interpretation for the quantitative value (muts/Mb). Cut-offs vary across assays and for each tumor type, so it is important to know which assay was used to determine the overall ordinal TMB result.

Cancer; Impression; Impression/interpretation of study; Impressions; Interp; Interpretation; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Mut; Mutations; Ordinal; Point in time; QL; Qual; Qualitative; Random; Screen; TMB; Tumor mutational load; tumors; tumour; tumours

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Tumor mutation burden Ql (Tumor) [Interp]Tumor mutation burden [Interpretation]TMB Tumor-ImpTumor mutation burdenMOLPATH.MUTTumor mutation burden, TumorImp

Frequently asked questions

Code details

Code94077-5

SystemLOINC

Display nameTumor mutation burden Ql (Tumor) [Interp]

DescriptionTumor mutation burden

Short nameTMB Tumor-Imp

ComponentTumor mutation burden

PropertyImp

TimingPt

System (specimen)Tumor

ScaleOrd

ClassMOLPATH.MUT

StatusACTIVE

Order/ObservationBoth

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.67

Last changed2.67

Consumer names

Tumor mutation burden, Tumor

Part names

Tumor mutation burdenImpPtTumorOrdImpression/interpretation of studyPoint in time (spot)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.