LOINC Code 94442-1: HLA-A & B & C (class I) Ab.IgG with prozone effect FC Nom

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component HLA-A & B & C (class I) Ab.IgG with prozone effect. It is commonly used with the system or sample type Ser/Plas.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Observation
• Method: Flow cytometry

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• HLA-A and B and C (class I) IgG with prozone effect [Identifier] in Serum or Plasma by Flow cytometry (FC)
• HLA-A & B & C (class I) Ab.IgG with prozone effect
• Sometimes high titer antibody can be associated with low levels of detection (low mean fluorescence intensity, MFI, for the Luminex HLA bead assay), a phenomenon often referred to as the "prozone" effect. This term is intended to report those antibodies that were not detected with original sample, but became detectable after dilution or assay treatment. Some laboratories refer to these "prozone antigens observed", meaning those antigens for which the patient's antibody exhibited prozone effect.
• A,B; Dynamic; FC; Genetics; Heredity; Heritable; HLA ANTIGEN; HLA class I; HLA class I Ab.IgG prozone; HLA-A+B; HLA-A+B+C; HLA-A+B+C (class I); Human Leukocyte Antigen; Identity or presence; Immune globulin G; Immunoglobulin G; Inherited; Nominal; Pl; Plasma; Plsm; Point in time; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions