ICD10BillableValid for clinical use
ICD-10 Code C49.A2: Gastrointestinal stromal tumor of stomach
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents gastrointestinal stromal tumor of stomach in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C00-C75Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue
block
C45-C49Malignant neoplasms of mesothelial and soft tissue
category
C49Malignant neoplasm of other connective and soft tissue
category
C49.AGastrointestinal stromal tumor
currentC49.A
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral PhysicianGastroenterologist
Related codes
C49.A0Gastrointestinal stromal tumor, unspecified sitecodeC49.A1Gastrointestinal stromal tumor of esophaguscodeC49.A3Gastrointestinal stromal tumor of small intestinecodeC49.A4Gastrointestinal stromal tumor of large intestinecodeC49.A5Gastrointestinal stromal tumor of rectumcodeC49.A9Gastrointestinal stromal tumor of other sitescode
Sibling codes
C49.A0Gastrointestinal stromal tumor, unspecified sitebillableC49.A1Gastrointestinal stromal tumor of esophagusbillableC49.A3Gastrointestinal stromal tumor of small intestinebillableC49.A4Gastrointestinal stromal tumor of large intestinebillableC49.A5Gastrointestinal stromal tumor of rectumbillableC49.A9Gastrointestinal stromal tumor of other sitesbillable
Coverage-related procedures and services
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81445high
SOLID ORGAN NEOPLASM, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS AND COPY NUMBER VARIANTS OR REARRANGEMENTS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 0543Uhigh
ONCOLOGY (SOLID TUMOR), NEXT-GENERATION SEQUENCING OF DNA FROM FORMALIN-FIXED PARAFFIN-EMBEDDED (FFPE) TISSUE OF 517 GENES, INTERROGATION FOR SINGLE-NUCLEOTIDE VARIANTS, MULTI-NUCLEOTIDE VARIANTS, INSERTIONS AND DELETIONS FROM DNA, FUSIONS IN 24 GENES AND SPLICE VARIANTS IN 1 GENE FROM RNA, AND TUMOR MUTATION BURDEN
Source: CMS coverage guidance
CPT 0329Uhigh
ONCOLOGY (NEOPLASIA), EXOME AND TRANSCRIPTOME SEQUENCE ANALYSIS FOR SEQUENCE VARIANTS, GENE COPY NUMBER AMPLIFICATIONS AND DELETIONS, GENE REARRANGEMENTS, MICROSATELLITE INSTABILITY AND TUMOR MUTATIONAL BURDEN UTILIZING DNA AND RNA FROM TUMOR WITH DNA FROM NORMAL BLOOD OR SALIVA FOR SUBTRACTION, REPORT OF CLINICALLY SIGNIFICANT MUTATION(S) WITH THERAPY ASSOCIATIONS
Source: CMS coverage guidance
CPT 0250Uhigh
ONCOLOGY (SOLID ORGAN NEOPLASM), TARGETED GENOMIC SEQUENCE DNA ANALYSIS OF 505 GENES, INTERROGATION FOR SOMATIC ALTERATIONS (SNVS [SINGLE NUCLEOTIDE VARIANT], SMALL INSERTIONS AND DELETIONS, ONE AMPLIFICATION, AND FOUR TRANSLOCATIONS), MICROSATELLITE INSTABILITY AND TUMOR-MUTATION BURDEN
Source: CMS coverage guidance
CPT 0244Uhigh
ONCOLOGY (SOLID ORGAN), DNA, COMPREHENSIVE GENOMIC PROFILING, 257 GENES, INTERROGATION FOR SINGLE-NUCLEOTIDE VARIANTS, INSERTIONS/DELETIONS, COPY NUMBER ALTERATIONS, GENE REARRANGEMENTS, TUMOR-MUTATIONAL BURDEN AND MICROSATELLITE INSTABILITY, UTILIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TUMOR TISSUE
Source: CMS coverage guidance
Coding guidelines
Common synonyms
Gastrointestinal stromal tumor of stomach
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.