ICD10BillableValid for clinical use

ICD-10 Code D49.2: Neoplasm of unspecified behavior of bone, soft tissue, and skin

D49.2 is a billable ICD-10 diagnosis code used to classify Neoplasm of unspecified behavior of bone, soft tissue, and skin in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

When is it used?

  • May be used when a clinician documents neoplasm of unspecified behavior of bone, soft tissue, and skin in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
2Neoplasms (C00-D49)
block
D49Neoplasms of unspecified behavior (D49)
category
D49Neoplasms of unspecified behavior
currentD49

Official coding notes

Excludes1 (do not code together)
  • neoplasm of unspecified behavior of anal canal (D49.0)
  • neoplasm of unspecified behavior of anus NOS (D49.0)
  • neoplasm of unspecified behavior of bone marrow (D49.89)
  • neoplasm of unspecified behavior of cartilage of larynx (D49.1)
  • neoplasm of unspecified behavior of cartilage of nose (D49.1)
  • neoplasm of unspecified behavior of connective tissue of breast (D49.3)
  • neoplasm of unspecified behavior of skin of genital organs (D49.59)
  • neoplasm of unspecified behavior of vermilion border of lip (D49.0)

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

OncologistGeneral PhysicianDermatologist

Coverage-related procedures and services

CPT 81540high
ONCOLOGY (TUMOR OF UNKNOWN ORIGIN), MRNA, GENE EXPRESSION PROFILING BY REAL-TIME RT-PCR OF 92 GENES (87 CONTENT AND 5 HOUSEKEEPING) TO CLASSIFY TUMOR INTO MAIN CANCER TYPE AND SUBTYPE, UTILIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE, ALGORITHM REPORTED AS A PROBABILITY OF A PREDICTED MAIN CANCER TYPE AND SUBTYPE
Source: CMS coverage guidance
CPT 17111high
DESTRUCTION (EG, LASER SURGERY, ELECTROSURGERY, CRYOSURGERY, CHEMOSURGERY, SURGICAL CURETTEMENT), OF BENIGN LESIONS OTHER THAN SKIN TAGS OR CUTANEOUS VASCULAR PROLIFERATIVE LESIONS; 15 OR MORE LESIONS
Source: CMS coverage guidance
CPT 17110high
DESTRUCTION (EG, LASER SURGERY, ELECTROSURGERY, CRYOSURGERY, CHEMOSURGERY, SURGICAL CURETTEMENT), OF BENIGN LESIONS OTHER THAN SKIN TAGS OR CUTANEOUS VASCULAR PROLIFERATIVE LESIONS; UP TO 14 LESIONS
Source: CMS coverage guidance
CPT 11420high
EXCISION, BENIGN LESION INCLUDING MARGINS, EXCEPT SKIN TAG (UNLESS LISTED ELSEWHERE), SCALP, NECK, HANDS, FEET, GENITALIA; EXCISED DIAMETER 0.5 CM OR LESS
Source: CMS coverage guidance
CPT 11421high
EXCISION, BENIGN LESION INCLUDING MARGINS, EXCEPT SKIN TAG (UNLESS LISTED ELSEWHERE), SCALP, NECK, HANDS, FEET, GENITALIA; EXCISED DIAMETER 0.6 TO 1.0 CM
Source: CMS coverage guidance
CPT 11422high
EXCISION, BENIGN LESION INCLUDING MARGINS, EXCEPT SKIN TAG (UNLESS LISTED ELSEWHERE), SCALP, NECK, HANDS, FEET, GENITALIA; EXCISED DIAMETER 1.1 TO 2.0 CM
Source: CMS coverage guidance

Coding guidelines

Common synonyms

Neoplasm of unspecified behavior of bone, soft tissue, and skinNeoplasm of behavior of bone, soft tissue, and skin

Frequently asked questions

Code details

CodeD49.2
SystemICD10
Display nameNeoplasm of unspecified behavior of bone, soft tissue, and skin
ChapterNeoplasms (C00-D49)
BlockNeoplasms of unspecified behavior (D49)

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
OsteitisOsteitisOsteitisOsteitisOsteitisOsteitisOsteitisOsteitisOsteitisOsteitisOsteitisOsteitis

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code D49.2 for Neoplasm of unspecified behavior of bone, soft tissue, and skin | HealthAssure