ICD10BillableValid for clinical use
ICD-10 Code E16.0: Drug-induced hypoglycemia without coma
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents drug-induced hypoglycemia without coma in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E15-E16Other disorders of glucose regulation and pancreatic internal secretion
category
E16Other disorders of pancreatic internal secretion
currentE16
Official coding notes
Applicable to
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- code for hypoglycemia level, if applicable (E16.A-)
Excludes1 (do not code together)
- diabetes with hypoglycemia without coma (E09.649)
Use additional code
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- code for hypoglycemia level, if applicable (E16.A-)
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
E16.1Other hypoglycemiacodeE16.2Hypoglycemia, unspecifiedcodeE16.3Increased secretion of glucagoncodeE16.4Increased secretion of gastrincodeE16.8Other specified disorders of pancreatic internal secretioncodeE16.9Disorder of pancreatic internal secretion, unspecifiedcodeE16.AHypoglycemia levelcategory
Sibling codes
E16.1Other hypoglycemiabillableE16.2Hypoglycemia, unspecifiedbillableE16.3Increased secretion of glucagonbillableE16.4Increased secretion of gastrinbillableE16.8Other specified disorders of pancreatic internal secretionbillableE16.9Disorder of pancreatic internal secretion, unspecifiedbillableE16.AHypoglycemia level
Coverage-related procedures and services
CPT 00532high
ANESTHESIA FOR ACCESS TO CENTRAL VENOUS CIRCULATION
Source: CMS coverage guidance
CPT 01420high
ANESTHESIA FOR ALL CAST APPLICATIONS, REMOVAL, OR REPAIR INVOLVING KNEE JOINT
Source: CMS coverage guidance
CPT 01730high
ANESTHESIA FOR ALL CLOSED PROCEDURES ON HUMERUS AND ELBOW
Source: CMS coverage guidance
CPT 01380high
ANESTHESIA FOR ALL CLOSED PROCEDURES ON KNEE JOINT
Source: CMS coverage guidance
CPT 01820high
ANESTHESIA FOR ALL CLOSED PROCEDURES ON RADIUS, ULNA, WRIST, OR HAND BONES
Source: CMS coverage guidance
CPT 00322high
ANESTHESIA FOR ALL PROCEDURES ON ESOPHAGUS, THYROID, LARYNX, TRACHEA AND LYMPHATIC SYSTEM OF NECK; NEEDLE BIOPSY OF THYROID
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 237646004high
Drug-induced hyperinsulinemia
Source: SNOMED International ICD-10 map
SNOMED_CT 237640005high
Drug-induced hypoglycemia
Source: SNOMED International ICD-10 map
SNOMED_CT 190448007high
Drug-induced hypoglycemia without coma
Source: SNOMED International ICD-10 map
SNOMED_CT 1137328006high
Iatrogenic hypoglycaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 84361000119102high
Insulin reactive hypoglycaemia due to type 2 diabetes mellitus
Source: SNOMED International ICD-10 map
SNOMED_CT 838320004high
Autonomic neuropathy due to medication induced hypoglycemia
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E16.0
Common synonyms
Drug-induced hypoglycemia without coma
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.