ICD10BillableValid for clinical use
ICD-10 Code E72.4: Disorders of ornithine metabolism
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents disorders of ornithine metabolism in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E72Other disorders of amino-acid metabolism
currentE72
Official coding notes
Inclusion terms
- Hyperammonemia-Hyperornithinemia-Homocitrullinemia syndrome
- Ornithinemia (types I, II)
- Ornithine transcarbamylase deficiency
Excludes1 (do not code together)
- hereditary choroidal dystrophy (H31.2-)
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
E72.0Disorders of amino-acid transportcategoryE72.1Disorders of sulfur-bearing amino-acid metabolismcategoryE72.2Disorders of urea cycle metabolismcategoryE72.3Disorders of lysine and hydroxylysine metabolismcodeE72.5Disorders of glycine metabolismcategoryE72.8Other specified disorders of amino-acid metabolismcategoryE72.9Disorder of amino-acid metabolism, unspecifiedcode
Sibling codes
E72.0Disorders of amino-acid transportE72.1Disorders of sulfur-bearing amino-acid metabolismE72.2Disorders of urea cycle metabolismE72.3Disorders of lysine and hydroxylysine metabolismbillableE72.5Disorders of glycine metabolismE72.8Other specified disorders of amino-acid metabolismE72.9Disorder of amino-acid metabolism, unspecifiedbillable
Mapped diagnoses and classifications
SNOMED_CT 237928008high
Disorder of ornithine metabolism
Source: SNOMED International ICD-10 map
SNOMED_CT 1222658006high
Global developmental delay, alopecia, macrocephaly, facial dysmorphism, structural brain anomalies syndrome
Source: SNOMED International ICD-10 map
SNOMED_CT 33985005high
Hyperornithinemia
Source: SNOMED International ICD-10 map
SNOMED_CT 30287008high
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome
Source: SNOMED International ICD-10 map
SNOMED_CT 276426004high
Ornithine aminotransferase deficiency
Source: SNOMED International ICD-10 map
SNOMED_CT 80908008high
Ornithine carbamoyltransferase deficiency
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E72.4
Common synonyms
Disorders of ornithine metabolism
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.