ICD10BillableValid for clinical use

ICD-10 Code G31.81: Alpers disease

G31.81 is a billable ICD-10 diagnosis code used to classify Alpers disease in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the nervous system (G00-G99).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the nervous system (G00-G99).

When is it used?

  • May be used when a clinician documents alpers disease in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
6Diseases of the nervous system (G00-G99)
block
G30-G32Other degenerative diseases of the nervous system
category
G31Other degenerative diseases of nervous system, not elsewhere classified
category
G31.8Other specified degenerative diseases of nervous system
currentG31.8

Official coding notes

Inclusion terms
  • Grey-matter degeneration

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

NeurologistGeneral Physician

Coding guidelines

Common synonyms

Alpers disease

Frequently asked questions

Code details

CodeG31.81
SystemICD10
Display nameAlpers disease
ChapterDiseases of the nervous system (G00-G99)
BlockOther degenerative diseases of the nervous system

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Alpers' diseaseDegeneration, degenerative

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code G31.81 for Alpers disease | HealthAssure