ICD10BillableValid for clinical use
ICD-10 Code L51.2: Toxic epidermal necrolysis [Lyell]
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the skin and subcutaneous tissue (L00-L99).
When is it used?
- May be used when a clinician documents toxic epidermal necrolysis [lyell] in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
12Diseases of the skin and subcutaneous tissue (L00-L99)
block
L49-L54Urticaria and erythema
category
L51Erythema multiforme
currentL51
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
Dermatologist
Related codes
Sibling codes
Coverage-related procedures and services
HCPCS J1552high
INJECTION, IMMUNE GLOBULIN (ALYGLO), 500 MG
Source: CMS coverage guidance
HCPCS J1554high
INJECTION, IMMUNE GLOBULIN (ASCENIV), 500 MG
Source: CMS coverage guidance
HCPCS J1556high
INJECTION, IMMUNE GLOBULIN (BIVIGAM), 500 MG
Source: CMS coverage guidance
HCPCS J1576high
INJECTION, IMMUNE GLOBULIN (PANZYGA), INTRAVENOUS, NON-LYOPHILIZED (E.G., LIQUID), 500 MG
Source: CMS coverage guidance
HCPCS J1459high
INJECTION, IMMUNE GLOBULIN (PRIVIGEN), INTRAVENOUS, NON-LYOPHILIZED (E.G., LIQUID), 500 MG
Source: CMS coverage guidance
HCPCS J1553high
INJECTION, IMMUNE GLOBULIN (YIMMUGO), 100 MG
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 768962006high
Lyell syndrome
Source: SNOMED International ICD-10 map
SNOMED_CT 768946000high
Stevens-Johnson syndrome, toxic epidermal necrolysis spectrum
Source: SNOMED International ICD-10 map
SNOMED_CT 402744003high
Toxic epidermal necrolysis caused by drug
Source: SNOMED International ICD-10 map
SNOMED_CT 402359006high
Toxic epidermal necrolysis due to graft-versus-host disease
Source: SNOMED International ICD-10 map
SNOMED_CT 768961004high
Toxic epidermal necrolysis due to infection
Source: SNOMED International ICD-10 map
SNOMED_CT 124911000119100high
Stevens Johnson syndrome AND toxic epidermal necrolysis overlap
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
L51.2
Common synonyms
Toxic epidermal necrolysis [Lyell]
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.