What does ICD-10 code E16 mean?

ICD-10 code E16 is the standardized code used for other disorders of pancreatic internal secretion in medical records and coding systems.

When is ICD-10 code E16 used?

Doctors, hospitals, and insurers may use ICD-10 code E16 when recording other disorders of pancreatic internal secretion in a standardized format. This entry may also act as a broader category that points toward more specific child codes.

Does ICD-10 code E16 confirm a diagnosis?

No. A code helps standardize documentation and claims, but it should not be read as a substitute for a clinician's full assessment.

ICD10

ICD-10 Code E16: Other disorders of pancreatic internal secretion

Name: ICD-10 Code E16: Other disorders of pancreatic internal secretion
Creator: HealthAssure Clinical Team
Published: 2026-05-21T06:05:02.297Z

E16 is an ICD-10 diagnosis entry used to group records related to Other disorders of pancreatic internal secretion. You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen. ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

When is it used?

May be used when a clinician documents other disorders of pancreatic internal secretion in a patient's medical record.
May appear in hospital records, claims, referrals, and clinical documentation.
This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.

What it does not mean

A code alone does not explain severity, treatment plan, or outcome.
A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
This entry may represent a broader category rather than the most specific billable code.

Code hierarchy

chapter

4Endocrine, nutritional and metabolic diseases (E00-E89)

block

E15-E16Other disorders of glucose regulation and pancreatic internal secretion

currentE15-E16

Where you may see this code

You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.

Related specialists

EndocrinologistGeneral Physician

Sibling codes

E15Nondiabetic hypoglycemic comabillable

Coding guidelines

Compatibility

Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.

Legacy codes

E16

Replacement codes

E16.0 — Drug-induced hypoglycemia without comaE16.1 — Other hypoglycemiaE16.2 — Hypoglycemia, unspecifiedE16.3 — Increased secretion of glucagonE16.4 — Increased secretion of gastrinE16.8 — Other specified disorders of pancreatic internal secretionE16.9 — Disorder of pancreatic internal secretion, unspecified

Common synonyms

Other disorders of pancreatic internal secretion

Frequently asked questions

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.