ICD10BillableValid for clinical use

ICD-10 Code E85.1: Neuropathic heredofamilial amyloidosis

E85.1 is a billable ICD-10 diagnosis code used to classify Neuropathic heredofamilial amyloidosis in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

When is it used?

  • May be used when a clinician documents neuropathic heredofamilial amyloidosis in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E85Amyloidosis
currentE85

Official coding notes

Inclusion terms
  • Amyloid polyneuropathy (Portuguese)
  • Transthyretin-related (ATTR) familial amyloid polyneuropathy

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

EndocrinologistGeneral Physician

Coverage-related procedures and services

CPT 11720high
DEBRIDEMENT OF NAIL(S) BY ANY METHOD(S); 1 TO 5
Source: CMS coverage guidance
CPT 11721high
DEBRIDEMENT OF NAIL(S) BY ANY METHOD(S); 6 OR MORE
Source: CMS coverage guidance
HCPCS G0127high
TRIMMING OF DYSTROPHIC NAILS, ANY NUMBER
Source: CMS coverage guidance
CPT 11719high
TRIMMING OF NONDYSTROPHIC NAILS, ANY NUMBER
Source: CMS coverage guidance
CPT 81404high
MOLECULAR PATHOLOGY PROCEDURE, LEVEL 5 (EG, ANALYSIS OF 2-5 EXONS BY DNA SEQUENCE ANALYSIS, MUTATION SCANNING OR DUPLICATION/DELETION VARIANTS OF 6-10 EXONS, OR CHARACTERIZATION OF A DYNAMIC MUTATION DISORDER/TRIPLET REPEAT BY SOUTHERN BLOT ANALYSIS) UGT1A1 (UDP GLUCURONOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1) (EG, HEREDITARY UNCONJUGATED HYPERBILIRUBINEMIA [CRIGLER-NAJJAR SYNDROME]) FULL GENE SEQUENCE
Source: CMS coverage guidance
CPT 11056high
PARING OR CUTTING OF BENIGN HYPERKERATOTIC LESION (EG, CORN OR CALLUS); 2 TO 4 LESIONS
Source: CMS coverage guidance

Coding guidelines

Compatibility

Legacy and official ICD code match exactly.
Legacy codes
E85.1

Common synonyms

Neuropathic heredofamilial amyloidosis

Frequently asked questions

Code details

CodeE85.1
SystemICD10
Display nameNeuropathic heredofamilial amyloidosis
ChapterEndocrine, nutritional and metabolic diseases (E00-E89)
BlockMetabolic disorders

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Amyloidosis(generalized) (primary)Amyloidosis(generalized) (primary)Polyneuropathy(peripheral)Polyneuropathy(peripheral)Polyneuropathy(peripheral)Polyneuropathy(peripheral)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code E85.1 for Neuropathic heredofamilial amyloidosis | HealthAssure