ICD10BillableValid for clinical use
ICD-10 Code E85.3: Secondary systemic amyloidosis
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents secondary systemic amyloidosis in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E85Amyloidosis
currentE85
Official coding notes
Inclusion terms
- Hemodialysis-associated amyloidosis
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
Sibling codes
Coverage-related procedures and services
CPT 11720high
DEBRIDEMENT OF NAIL(S) BY ANY METHOD(S); 1 TO 5
Source: CMS coverage guidance
CPT 11721high
DEBRIDEMENT OF NAIL(S) BY ANY METHOD(S); 6 OR MORE
Source: CMS coverage guidance
HCPCS G0127high
TRIMMING OF DYSTROPHIC NAILS, ANY NUMBER
Source: CMS coverage guidance
CPT 11719high
TRIMMING OF NONDYSTROPHIC NAILS, ANY NUMBER
Source: CMS coverage guidance
CPT 81404high
MOLECULAR PATHOLOGY PROCEDURE, LEVEL 5 (EG, ANALYSIS OF 2-5 EXONS BY DNA SEQUENCE ANALYSIS, MUTATION SCANNING OR DUPLICATION/DELETION VARIANTS OF 6-10 EXONS, OR CHARACTERIZATION OF A DYNAMIC MUTATION DISORDER/TRIPLET REPEAT BY SOUTHERN BLOT ANALYSIS) UGT1A1 (UDP GLUCURONOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1) (EG, HEREDITARY UNCONJUGATED HYPERBILIRUBINEMIA [CRIGLER-NAJJAR SYNDROME]) FULL GENE SEQUENCE
Source: CMS coverage guidance
CPT 11056high
PARING OR CUTTING OF BENIGN HYPERKERATOTIC LESION (EG, CORN OR CALLUS); 2 TO 4 LESIONS
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 69078007high
Age-related amyloidosis
Source: SNOMED International ICD-10 map
SNOMED_CT 1187540008high
Cardiac secondary systemic amyloidosis
Source: SNOMED International ICD-10 map
SNOMED_CT 1187538003high
Cerebral secondary systemic amyloid angiopathy
Source: SNOMED International ICD-10 map
SNOMED_CT 1187553006high
Glomerular disorder due to secondary systemic amyloidosis
Source: SNOMED International ICD-10 map
SNOMED_CT 402458002high
Haemodialysis-associated secondary amyloidosis of skin
Source: SNOMED International ICD-10 map
SNOMED_CT 32599008high
Hemodialysis-associated amyloidosis
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E85.3
Common synonyms
Secondary systemic amyloidosis
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.