ICD10BillableValid for clinical use
ICD-10 Code E88.A: Wasting disease (syndrome) due to underlying condition
Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents wasting disease (syndrome) due to underlying condition in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E88Other and unspecified metabolic disorders
currentE88
Official coding notes
Inclusion terms
- Cachexia due to underlying condition
Applicable to
- underlying condition
Excludes1 (do not code together)
- cachexia NOS (R64)
- nutritional marasmus (E41)
Excludes2 (may code together if documented)
- failure to thrive (R62.51, R62.7)
Code first
- underlying condition
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
E88.0Disorders of plasma-protein metabolism, not elsewhere classifiedcategoryE88.1Lipodystrophy, not elsewhere classifiedcategoryE88.2Lipomatosis, not elsewhere classifiedcodeE88.3Tumor lysis syndromecodeE88.4Mitochondrial metabolism disorderscategoryE88.8Other specified metabolic disorderscategoryE88.9Metabolic disorder, unspecifiedcode
Sibling codes
E88.0Disorders of plasma-protein metabolism, not elsewhere classifiedE88.1Lipodystrophy, not elsewhere classifiedE88.2Lipomatosis, not elsewhere classifiedbillableE88.3Tumor lysis syndromebillableE88.4Mitochondrial metabolism disordersE88.8Other specified metabolic disordersE88.9Metabolic disorder, unspecifiedbillable
Coding guidelines
Common synonyms
Wasting disease (syndrome) due to underlying conditionWasting diseaseWasting disease syndrome due to underlying condition
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.