ICD10BillableValid for clinical use
ICD-10 Code E27.3: Drug-induced adrenocortical insufficiency
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents drug-induced adrenocortical insufficiency in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E20-E35Disorders of other endocrine glands
category
E27Other disorders of adrenal gland
currentE27
Official coding notes
Applicable to
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Use additional code
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
E27.0Other adrenocortical overactivitycodeE27.1Primary adrenocortical insufficiencycodeE27.2Addisonian crisiscodeE27.4Other and unspecified adrenocortical insufficiencycategoryE27.5Adrenomedullary hyperfunctioncodeE27.8Other specified disorders of adrenal glandcodeE27.9Disorder of adrenal gland, unspecifiedcode
Sibling codes
E27.0Other adrenocortical overactivitybillableE27.1Primary adrenocortical insufficiencybillableE27.2Addisonian crisisbillableE27.4Other and unspecified adrenocortical insufficiencyE27.5Adrenomedullary hyperfunctionbillableE27.8Other specified disorders of adrenal glandbillableE27.9Disorder of adrenal gland, unspecifiedbillable
Coverage-related procedures and services
CPT 00532high
ANESTHESIA FOR ACCESS TO CENTRAL VENOUS CIRCULATION
Source: CMS coverage guidance
CPT 01420high
ANESTHESIA FOR ALL CAST APPLICATIONS, REMOVAL, OR REPAIR INVOLVING KNEE JOINT
Source: CMS coverage guidance
CPT 01730high
ANESTHESIA FOR ALL CLOSED PROCEDURES ON HUMERUS AND ELBOW
Source: CMS coverage guidance
CPT 01380high
ANESTHESIA FOR ALL CLOSED PROCEDURES ON KNEE JOINT
Source: CMS coverage guidance
CPT 01820high
ANESTHESIA FOR ALL CLOSED PROCEDURES ON RADIUS, ULNA, WRIST, OR HAND BONES
Source: CMS coverage guidance
CPT 00322high
ANESTHESIA FOR ALL PROCEDURES ON ESOPHAGUS, THYROID, LARYNX, TRACHEA AND LYMPHATIC SYSTEM OF NECK; NEEDLE BIOPSY OF THYROID
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 1345094006high
Anabolic steroid withdrawal syndrome following harmful pattern of use
Source: SNOMED International ICD-10 map
SNOMED_CT 1345095007high
Corticosteroid withdrawal syndrome following harmful pattern of use
Source: SNOMED International ICD-10 map
SNOMED_CT 1345092005high
Corticosteroid withdrawal syndrome following therapeutic use
Source: SNOMED International ICD-10 map
SNOMED_CT 190524001high
Drug-induced adrenocortical insufficiency
Source: SNOMED International ICD-10 map
SNOMED_CT 237763005high
Iatrogenic adrenal insufficiency
Source: SNOMED International ICD-10 map
SNOMED_CT 1345090002high
Steroid hormone withdrawal syndrome following harmful pattern of use
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E27.3
Common synonyms
Drug-induced adrenocortical insufficiency
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.