ICD10BillableValid for clinical use
ICD-10 Code E78.1: Pure hyperglyceridemia
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents pure hyperglyceridemia in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E78Disorders of lipoprotein metabolism and other lipidemias
currentE78
Official coding notes
Inclusion terms
- Elevated fasting triglycerides
- Endogenous hyperglyceridemia
- Fredrickson's hyperlipoproteinemia, type IV
- Hyperlipidemia, group B
- Hyperprebetalipoproteinemia
- Very-low-density-lipoprotein-type [VLDL] hyperlipoproteinemia
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
E78.0Pure hypercholesterolemiacategoryE78.2Mixed hyperlipidemiacodeE78.3HyperchylomicronemiacodeE78.4Other hyperlipidemiacategoryE78.5Hyperlipidemia, unspecifiedcodeE78.6Lipoprotein deficiencycodeE78.7Disorders of bile acid and cholesterol metabolismcategoryE78.8Other disorders of lipoprotein metabolismcategoryE78.9Disorder of lipoprotein metabolism, unspecifiedcode
Sibling codes
E78.0Pure hypercholesterolemiaE78.2Mixed hyperlipidemiabillableE78.3HyperchylomicronemiabillableE78.4Other hyperlipidemiaE78.5Hyperlipidemia, unspecifiedbillableE78.6Lipoprotein deficiencybillableE78.7Disorders of bile acid and cholesterol metabolismE78.8Other disorders of lipoprotein metabolismE78.9Disorder of lipoprotein metabolism, unspecifiedbillable
Coverage-related procedures and services
CPT 0349Uhigh
DRUG METABOLISM OR PROCESSING (MULTIPLE CONDITIONS), WHOLE BLOOD OR BUCCAL SPECIMEN, DNA ANALYSIS, 27 GENE REPORT, WITH VARIANT ANALYSIS, INCLUDING REPORTED PHENOTYPES AND IMPACTED GENE-DRUG INTERACTIONS
Source: CMS coverage guidance
CPT 0423Uhigh
PSYCHIATRY (EG, DEPRESSION, ANXIETY), GENOMIC ANALYSIS PANEL, INCLUDING VARIANT ANALYSIS OF 26 GENES, BUCCAL SWAB, REPORT INCLUDING METABOLIZER STATUS AND RISK OF DRUG TOXICITY BY CONDITION
Source: CMS coverage guidance
CPT 83090high
HOMOCYSTEINE
Source: CMS coverage guidance
CPT 83698high
LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 (LP-PLA2)
Source: CMS coverage guidance
CPT 82172high
APOLIPOPROTEIN, EACH
Source: CMS coverage guidance
CPT 86141high
C-REACTIVE PROTEIN; HIGH SENSITIVITY (HSCRP)
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 129589009high
Endogenous hyperlipidaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 34528009high
Familial hypertriglyceridemia
Source: SNOMED International ICD-10 map
SNOMED_CT 238085009high
Fredrickson type IV hyperlipoproteinemia
Source: SNOMED International ICD-10 map
SNOMED_CT 302870006high
Hypertriglyceridaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 402785008high
Primary genetic hyperlipidaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 238083002high
Primary hypertriglyceridaemia
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E78.1
Common synonyms
Pure hyperglyceridemia
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.