ICD10BillableValid for clinical use
ICD-10 Code E78.6: Lipoprotein deficiency
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents lipoprotein deficiency in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E78Disorders of lipoprotein metabolism and other lipidemias
currentE78
Official coding notes
Inclusion terms
- Abetalipoproteinemia
- Depressed HDL cholesterol
- High-density lipoprotein deficiency
- Hypoalphalipoproteinemia
- Hypobetalipoproteinemia (familial)
- Lecithin cholesterol acyltransferase deficiency
- Tangier disease
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
E78.0Pure hypercholesterolemiacategoryE78.1Pure hyperglyceridemiacodeE78.2Mixed hyperlipidemiacodeE78.3HyperchylomicronemiacodeE78.4Other hyperlipidemiacategoryE78.5Hyperlipidemia, unspecifiedcodeE78.7Disorders of bile acid and cholesterol metabolismcategoryE78.8Other disorders of lipoprotein metabolismcategoryE78.9Disorder of lipoprotein metabolism, unspecifiedcode
Sibling codes
E78.0Pure hypercholesterolemiaE78.1Pure hyperglyceridemiabillableE78.2Mixed hyperlipidemiabillableE78.3HyperchylomicronemiabillableE78.4Other hyperlipidemiaE78.5Hyperlipidemia, unspecifiedbillableE78.7Disorders of bile acid and cholesterol metabolismE78.8Other disorders of lipoprotein metabolismE78.9Disorder of lipoprotein metabolism, unspecifiedbillable
Coverage-related procedures and services
HCPCS G0255high
CURRENT PERCEPTION THRESHOLD/SENSORY NERVE CONDUCTION TEST, (SNCT) PER LIMB, ANY NERVE
Source: CMS coverage guidance
CPT 95905high
MOTOR AND/OR SENSORY NERVE CONDUCTION, USING PRECONFIGURED ELECTRODE ARRAY(S), AMPLITUDE AND LATENCY/VELOCITY STUDY, EACH LIMB, INCLUDES F-WAVE STUDY WHEN PERFORMED, WITH INTERPRETATION AND REPORT
Source: CMS coverage guidance
CPT 95907high
NERVE CONDUCTION STUDIES; 1-2 STUDIES
Source: CMS coverage guidance
CPT 95912high
NERVE CONDUCTION STUDIES; 11-12 STUDIES
Source: CMS coverage guidance
CPT 95913high
NERVE CONDUCTION STUDIES; 13 OR MORE STUDIES
Source: CMS coverage guidance
CPT 95908high
NERVE CONDUCTION STUDIES; 3-4 STUDIES
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 190787008high
Abetalipoproteinaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 250249008high
Acanthocytosis
Source: SNOMED International ICD-10 map
SNOMED_CT 238102008high
Apo A-I Giessen variant
Source: SNOMED International ICD-10 map
SNOMED_CT 238098000high
Apo A-I Marburg variant
Source: SNOMED International ICD-10 map
SNOMED_CT 238097005high
Apo A-I Milano variant
Source: SNOMED International ICD-10 map
SNOMED_CT 238103003high
Apo A-I variant fisheye-like syndrome
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E78.6
Common synonyms
Lipoprotein deficiency
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.